I recently beat cold blood after 2 dozen attempts and have decided to share my advice on how to handle it on higher difficulties.
Day 1 is the most important to get set up well with aphids. Immediately set your base workers to grab food and begin digging towards the entrance. Once you have 7 of them, put them all in group 1 and turn off collect food and battle. Once you have opened the entrance, immediately send them rushing towards the top left corner of aphids. There is a 50/50 chance they make it without being attacked on the way, it all depends on where enemies spawn. If they get caught up in battle, reset the game and try again. By this point you should have 12 aphids, just set your workers near it and let them gather, along with grabbing any loose food nearby.
Begin building 5-10 other workers and then build fire ant nests. Numbers matter more at this point. Once you have the workers built, begin making risky plays near the bottom to grab the other colony’s aphids. Keep upgrading and building until nightfall, and keep your fire ants on the aphid stalk to prevent any theft. Even a single aphid can make a massive difference at this point. Get at least a couple of tier 3 army ants by nightfall, you will need a good mix of levels and numbers to survive the frogs.
Keep collecting off the aphids and any loose food nearby, you aren’t strong enough to go out yet. In the base, break into the top left corner, and wherever else enemies spawn so frogs don’t release them. Eventually, frogs should break into your base. In order to cheese them in the beginning, set your workers to group 2 and your attackers to group 1.
Send group 2 to attack, until the toad does the grab attack. This attack kills many ants regardless of level, and also heals the frogs, and since ants fight head on it will decimate you at this early stage. However, this attack has a cool down. Once the cheap workers trigger it, rush in with your level 1-3 fire ants. They should be able to take the frogs before they do the grab attack again.
Once you have beaten the frogs, begin collecting aphid dew and make a play to grab any aphids you may have missed. Once you have grabbed most of them, make a play with all of your fire ants to the other aphid colony under yellow control. This should bring you up to around 19 aphids, although 1-2 lost during transport is fine. Keep collecting dew and expanding underground, although don’t kill every enemy underground, since some frog spawns take a while to get into base, which spreads them out and makes them easier to handle. Slowly kill enemies over time to gather food and reduce threat.
Relax a little, gather dew and fight off the constant waves of enemies. Grab any loose food and just keep upgrading and staying safe.
Survive the frog invasion once again. It will be harder this time, but if you didn’t kill all the enemies they should come in at a slow trickle rather than all at once. Once you have done this, you can try going to the islands in order to grab rogue aphids, if you have enough units to cross the water. The top right one is your closest and best bet for this night. Once you grab these (or don’t) just stay safe and keep collecting. Keep fire ants or those 5-10 workers on the aphid stalk at all times.
Again, stay safe. keep collecting dew and fending off attacks. You’re probably strong enough to attack a base now, but if you attack at daytime the other base will attack you. Fend off their attacks and stay alive.
Once you have handled the frog invasion, immediately begin gathering your army to go and attack blue base. They are the weaker and closer base, and this should be your first priority. Make sure you stop periodically on the march to let your ants clump together, you don’t want them trailing into the mouth of a salamander or rogue spider. Once you are nearby and all clumped up rush inside and immediately head for the queen. Once she is dead ignore the base, the food isn’t worth it. Grab their aphids near their base and bail. Collect any other aphids on islands you can and continue expanding below ground.
Continue staying safe and expanding. Expand everywhere underground now that you have less attacks coming, and beat all enemies there.
Beat off the frog invasion, and now it is time to attack yellow. If you don’t feel confident continue gathering aphids and loose food. The pine cone to the top left should be safe to grab now. You can attack on night 5 instead. Once you are confident though, destroy yellow base. They don’t have any aphids left at this point, and the food isn’t worth it, it will just free you up to fight the bullfrog in the morning.
Day 5: Bullfrog Time
Time to kill the behemoth. Put all your workers on dew collection, and begin attacking the bullfrog. If you have enough workers gathering dew and replanting eggs, it should be no trouble at all. Just keep spamming and swarming, and occasionally stop to clump your ants up. At this point it is just a matter of time, resources, and replacement. Just keep spamming your level 3 ants while collecting dew and placing eggs to replace any lost. At this point it should take half a day, but it is doable.
Congrats, you have likely just won. This strategy still has a lot of luck involved due to enemy spawns at the beginning and enemy movement patterns so it’s far from perfect. Just reset the game if you can’t win or get a good start.