The Binding of Isaac: Rebirth – Hard Mode Tips

Tips for Hard Mode

  • Memorize the attack patterns of enemies. If you dodge well, you should be able to get to the end of the floor with little health lost. Really the way to beat hard mode it to simply it play over and over again till you get good.
  • Every character has a different strategy. Try to figure out what these strategies are, and your life will get easier.
  • Learn which items are good, and which are bad. Some items that are normally good can break certain synergies, and some items that are normally bad can be good in certain situations.
  • Small stat boosts add up. The most important stats are generally damage and tears, and you should usually try to keep your speed stat > 1.
  • Try to get into the curse rooms as much as possible because they sometimes have powerful items. It is usually worth it if you have a lot of health or extra hearts laying around.
  • You can walk through the point where two spikes touch diagonally if you are really careful. Sometimes you can get items or pickups that are behind spikes by doing this.
  • If you’ve unlocked the Planetarium by collecting 3 different astrology related items in one run. It is sometimes a good idea to skip treasure rooms, because astrology room items are really good.
  • Look for stuff that gives you homing, such as Spoon Bender. Homing has some powerful synergies, and is especially helpful for new players.
Egor Opleuha
About Egor Opleuha 845 Articles
Egor Opleuha, also known as Juzzzie, is the Editor-in-Chief of Gameplay Tips and writer on Game Cheat Codes. He is a writer with more than 12 years of experience in writing and editing online content. His favorite game series was and still is the legendary Heroes of Might and Magic saga. And the third part of HOMM is his favorite! He prefers to spend all his free time playing retro games / indie games. When not immersed in games, Egor plays guitar, enjoys cooking and fishing.

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